Tumor tissue
Less than 25 percent tumor. Specimens fixed/processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). Decalcified specimens.
AMBIENT
Inactive both in IHC and ARUP
Varies
7-12 days
Polymerase Chain Reaction/Pyrosequencing
Core
IHC
Anti-EGFR therapy resistance testing
Cetuximab (Erbitux)
Codon 12,13
Codon 61
KRAS codons 12, 13, 61
Panitumumab (Vectibix)
RAS
Test
SPECIMEN PREPARATION: Tumor Tissue: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport tissue block or 5 unstained 5-micron slides. (Min: 3 slides) Transport block(s) and/or slide(s) in a tissue transport kit (ARUP Supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
81275; 81276
21702-6
