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Lung Cancer Limited Panel with KRAS

Specimen Collection Type

Tumor tissue

Stability

Ambient Stability: Unable
Refrig Stability: Unable
Frozen Stability: Unable

Unacceptable Conditions

Less than 25 percent tumor. Specimens fixed/processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). Decalcified specimens.

Preferred Transportation Temperature

AMBIENT

Remarks

Inactive both in IHC and ARUP

Performed

Varies

Reported

7-12 days

Methodology

Polymerase Chain Reaction/Pyrosequencing

Lab Department

Core

Testing Location

IHC

Synonyms

Anti-EGFR therapy resistance testing
Cetuximab (Erbitux)
Codon 12,13
Codon 61
KRAS codons 12, 13, 61
Panitumumab (Vectibix)
RAS

Test OR Panel

Test

Misc Instructions

SPECIMEN PREPARATION: Tumor Tissue: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport tissue block or 5 unstained 5-micron slides. (Min: 3 slides) Transport block(s) and/or slide(s) in a tissue transport kit (ARUP Supply #47808) available online through eSupply using ARUP Connectâ„¢ or contact ARUP Client Services at (800) 522-2787.

CPT Codes

81275; 81276

LOINC

21702-6

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